Creamy Swiss Chicken Casserole

Name: Creamy Swiss Chicken Casserole
Prep time: 10 min
Cook time: 30 min
Total time: 40 min
Ingredients: 2.5 pounds chicken breasts (boneless, skinless, cooked); 6 ounces Swiss cheese; 1/4 cup red or white wine; 1 can cream of chicken soup (10.5-ounce can); 1 box stuffing (6 ounce box); 6 tablespoons butter (melted)

TO RECIPE SAVE RECIPE

This post may contain affiliate links. Please read our disclosure policy.

Creamy Swiss Chicken Casserole is a super simple delicious dinner recipe! This creamy chicken bake recipe has 6 easy ingredients to help you get supper on the table in a hurry!

Packed with tender chicken, smothered in a mouth-watering cheesy creamy wine sauce, and topped off with a buttery stuffing mixture. This flavor combination makes for an irresistible chicken casserole everyone will love!

Why you’ll love this Swiss Chicken Bake recipe!

Super easy: 6 simple ingredients combined to make dinner easy.
Super tasty: Everyone, from kids to adults alike, just loves this creamy chicken bake recipe. It’s paked full of flavor!
Super fast: In the time it takes to saute your chicken, a quick stir and topping off of conveneience items. Then dinner is ready in no time.

I have been making this recipe most of my married life. I am not sure where it originally came from, but my friend Paton shared this recipe with me when she baked it for my family after the birth of my daughter.

Around here that’s what we do! Take care of our friends when they need a little help! And I am so glad she shared this with me.

It’s one my family loves and it’s a super simple weeknight dinner! And one that tastes good enough for Sunday supper too!

After all who doesn’t love wine and cheese together? I mean shouldn’t it be perfect for a chicken casserole?

Swiss Chicken Casserole Ingredients

Chicken – I start this with cooked chicken that I usually saute. But you can use boiled chicken, baked chicken, Instant Pot Chicken or even a rotisserie or left over chicken.
Swiss Cheese – I use sliced cheese, like you get in the deli or cheese section, for sandwiches, of the store.
Cream of Chicken Soup – Store bought classic or even low fat can be used. I typically use the orginal in this.
Wine – A nice crisp white wine thats not too sweet. A rich red works well too.
Stuffing – The boxed stuff is what I use (like Stove-Top). If you buy the bagged one you will only need about 2 cups.
Butter – I used a salted stick butter. I use 2 of the tablespoons to cook the chicken and 6 tablespoons for the topping. But it won’t hurt to use the whole stick on the topping 😉

How to make swiss chicken with stuffing and cheesy wine sauce

✱ Be sure to see the recipe card below for exact ingredients and full recipe instructions!

Preheat the oven to 350 degrees and grab a 9 X 13 casserole dish. You can also use an oven-safe pan and skip the casserole dish. I used a cast-iron skillet for this. (One less dish to wash!)

Step 1 | Pan fry chicken & prepare sauce

Pan fry your chicken in butter. Cook until they are no longer pink on the inside.

In a bowl mix together wine and cream of chicken soup.

Step 2 | Layer with Cheese, Sauce, & Stuffing

If needed transfer to a casserole dish and cover chicken evenly with swiss cheese.

Pour soup and wine mixture over the cheese layer.

Top with stuffing and drizzle butter on top! You can also toss the stuffing with the melted butter and then sprinkle on top.

Step 3| Bake & Serve

Bake for 20 to 30 minutes or until bubbly and stuffing is nicely browned! Since everything is cooked you are just getting that sauce nice and bubbly delicious!

Want to Save this Recipe?

Enter your email below & we'll send it straight to your inbox. Plus you’ll get great new recipes from us every week!

By submitting this form, you consent to receive emails from Soulfully Made.

Plate it up and serve with your favorite sides. It goes really well with rice pilaf, green beans, or a salad.

Frequently Asked Questions

Can I bake this without cooking the chicken first?

Yes, if you prefer to not cook the chicken you can prepare the casserole as instructed. Then cover the dish with foil and bake for 40 minutes. Remove foil and bake for 20 minutes uncovered. Be sure to check the internal temperature of the chicken (Chicken should be cooked to 165°F).

Can you use lighter ingredients in this dish?

Sure, if you want you can use a reduced-fat cheese and healthy request cream soup to lighten it up.

Variations or Add-Ins:

Want to change up the recipe for a little variety! Here are a few scrumptious suggestions.

Mushroom Swiss Chicken – Add a small can of your favorite mushrooms or 1 cup of fresh mushrooms into the soup mixture.
Swiss Chicken and Veggies – Add 2 cups of thawed broccoli, peas, carrots, or green beans into the soup mixture.
Changing the wine changes the flavor profile of the dish. This swiss chicken with white wine is (I usually use chardonnay) is also nice with a robust red wine too.
Change up the cheeses in this creamy swiss chicken casserole – While swiss cheese is the original, other cheeses are also very delicious in this dish. I recommend Gouda, Fontina, Mozzarella, and Provolone are also great choices.
Try different stuffing mixes. I buy the boxed stuffing mix and most often get the chicken flavor, but the cornbread, savory herb, and even the sage blend are awesome.

Use a cast-iron skillet or oven-safe pan for a one-dish easy clean-up.
Use a good quality chicken. This will mean the chicken is tender and delicious
Use full-fat original ingredients for the best flavor. This is a comfort dish. Lower fat items will work however, you will get a creamier texture and the richest flavor with full-fat ingredients.
You can use white or red wine. White wine lends a light crisp flavor while red wine gives the dish a bolder rich flavor. Both are equally delicious.
If you don’t cook with wine or do not have it, substitute with chicken broth or milk.

Tips

Storage:

Have any leftovers? You are in luck! These are so tasty the next day!

Leftovers:

Place in an air-tight container or separate in meal-sized portions and store:

Place in the refrigerator for 3 to 4 days.
To reheat, I recommend just heating in the microwave until heated through.
You can also freeze cooked leftovers for 1 month.

Freezer:

This recipe will freeze great for a make-ahead meal.

Place in a freezer-safe dish or foil casserole pan. Make as directed except do not put the stuffing mix on top. Then wrap with foil and plastic wrap and freeze for up to 4 months for the best flavor.

When ready to bake, thaw in the refrigerator for 24 hours, then prepare the stuffing topping and sprinkle over the top.

Bake as directed.

More Easy Casserole Recipes

If you loved this recipe, I hope you will take a moment to grab a few more recipes for your busy weeknight dinners. Pin or save them for later.

Check out more Main Dish Recipes here, or see a few reader’s favorites below.

Taco Spaghetti Casserole
Broccoli Cheddar Chicken Casserole (Cracker Barrel Copycat)
Mexican Stuffed Shells
Ground Beef and Sausage Rice Casserole
Baked Chicken Spaghetti

Hungry for more easy, home-cooked, delicious recipes?

Sign up for my free recipe club to get family-friendly recipes in your inbox each week! Find me sharing daily meal-time inspiration on Pinterest, Facebook, Instagram, and Twitter.

Update photos and added more helpful recipe tips & information on 9/1/2021

Cast-iron skillet with creamy swiss casserole being served with a serving spoon.

Recipe

Pin Print Rate Recipe Save

This Chicken Casserole with Wine & Cheese Sauce is an old family favorite. The flavors of the wine and cheese mix together well to create a rich and tasty casserole everyone will love.

Ingredients

▢ 2.5 pounds chicken breasts, boneless, skinless, cooked
▢ 6 ounces Swiss cheese
▢ ¼ cup red or white wine
▢ 1 can cream of chicken soup, 10.5-ounce can
▢ 1 box stuffing, 6 ounce box
▢ 6 tablespoons butter, melted